2 edition of Direct fluidised bed adsorption of protein products from complex particulate feedstocks found in the catalog.
Direct fluidised bed adsorption of protein products from complex particulate feedstocks
Gordon Roderick Gilchrist
Thesis (Ph.D) - University of Birmingham, School of Chemical Engineering, Faculty of Engineering.
|Statement||by Gordon Roderick Gilchrist.|
Abstract: A pressure-swing adsorption process, which uses zeolite 13X as an adsorbent to recover and sequester carbon dioxide from mixture gas (nitrogen and carbon dioxide), is investigated through dynamic simulation and optimization. The purpose of this paper is. CFD SIMULATION OF PHARMACEUTICAL PARTICLE DRYING IN A BUBBLING FLUIDIZED BED REACTOR heat and mass transfer phenomena of drying process in a bubbling fluidized bed was 1 Jang et al.: CFD SIMULATION OF PHARMACEUTICAL PARTICLE DRYING IN A BUBBLING FL Published by ECI Digital Archives, gas and particulate phase (see .
varying bed height. Also the maximum adsorption capacity increased with increase in flow rate and initial ion concentration but decreased with increase in bed height. Tamarind seeds adsorbent for removal of metals in a fixed bed were used by Suganthi . The removal of copper and cadmium in a fixed bed was studied by Size: KB. XPURE-E: Expanded Bed Adsorption. This purification process can be significantly improved using the Expanded Bed Adsorption (EBA) technology as can be observed on the right-hand side of the diagram. Whereas traditional column chromatography uses a packed resin bed, EBA uses an expanded bed.
allows the adsorption of the target protein directly from unclarified feedstock, such as culture suspensions, cell homogenates or crude extracts, while the remaining bioparticles freely pass through the bed that is expanded by an upward flow and . The primary objective of this work is to study the e ect of the particle size distribution on Expanded Bed Adsorption process. This is done by constructing a model which combines the hydrodynamics involved in bed expansion assuming a perfectly classi ed bed, with a model describing mass transport in an EBA process.
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Expanded bed adsorption has emerged as an efficient method for the recovery of products from complex feedstocks demonstrating advantages over the traditional methods of recovery, e.g. circumventing the need for clarification of feedstocks before application to a fixed bed chromatography column.
The growth of applications for Cited by: Fluidized bed adsorption has been introduced as an integrative technology combining clarification, concentration, and initial purification in a single step. In the paper presented here, the use of Cited by: Fabrication of a novel pellicular adsorbent customised for effective fluidised bed adsorption of protein products.
recovery of protein products from complex, particulate feedstocks (whole. Gilchrisit, Direct fluidised bed adsorption of protein products from complex particulate feedstocks, Ph.D. Thesis, University of Birmingham, Jan Hjorth R: Expanded-bed adsorption in industrial processing: recent developments.
Trends BiotechnolPerformance of adsorbents, feedstock contactors and modes of operation are described in the industrial scale recovery of Cited by: Gilchrist GR () Direct fluidised bed adsorption of protein products from complex particulate feedstocks: development of cellulose composites with selective binding properties.
Ph.D. Thesis, The University of Birmingham, by: Development of a Fluidized Bed System for Adsorption of Phenol 17 Brazilian Journal of Chemical Engineering Vol.
24, No. 01, pp. 15 - 28, January - March, point (process interruption), based on some criterion, either technical, economic or legal (Knaebel, ).
Expanded Bed Adsorption Expanded bed adsorption is a single pass operation in which desired proteins are purified from crude, particulate containing feed-stock without the need for separate clarification, concentration and initial purification.
The expansion of the adsorbent bed creates a distance between the adsorbent particals, i.e. increased File Size: KB. A fluidized bed is a physical phenomenon occurring when a quantity of a solid particulate substance (usually present in a holding vessel) is placed under appropriate conditions to cause a solid/fluid mixture to behave as a is usually achieved by the introduction of pressurized fluid through the particulate medium.
This results in the medium then having many properties. The mechanism of protein adsorption and resistance can be explained by several factors such as adsorption isotherms, thermodynamic equilibrium and adsorption kinetics.
Thermodynamic isotherms can be different from the experimental adsorption isotherms because the adsorbing surface is rapidly saturated and shows the limitation before reaching. Protein Adsorption by Filter Paper can be explained on the basis of other errors analytical tech- nique.
When small samples of cc. of serum must be analyzed, an approximate correction for loss due to adsorption is provided by adding gm. per cent to the final analytical result.
BIBLIOGRAPHY by: 6. A fluidized bed concentrator (FBC) is an industrial process for the treatment of exhaust system uses a bed of activated carbon beads to adsorb volatile organic compounds (VOCs) from the exhaust ng from the previous fixed-bed and carbon rotor concentrators, the FBC system forces the VOC-laden air through several perforated steel trays, increasing the velocity.
Scope of this Leading Opinion. Herein I review and broadly interpret approximately 25 years of my research into blood-protein adsorption. It is emphasized that blood proteins are the exclusive focus of this work and extrapolation of these results to other types of proteins dissolved in fluid phases other than high-ionic-strength aqueous-buffer solutions should be made with great Cited by: for Expanded Bed Adsorption (EBA).
T he concept of chromatography in Expanded Bed Adsorption (EBA) was first - proposed in early 90s.1 The initial advan-tage of the idea was to be able to directly process particulate containing biological feedstocks for target products, while still maintaining sufficiently high separation efficiency that is.
Adsorption Isotherms. The adsorption isotherm is a function that relates the measured adsorbed amount of a protein (per unit area), Γ p, to the solution concentration of protein, c lly, Γ p increases sharply at low solution concentrations of protein and levels off at higher protein concentrations approaching a limiting Γ p value.
The existence of a Γ p adsorption Cited by: Fluidised bed technology: Generating options for tomorrow Fluidisation-1 - Duration: Unit Operations of Particulate Mat views.
Fluidized Bed Reactor. Protein Capture by Expanded Bed Technology Adsorbent Materials The design of a special adsorbent is a key factor to enhance the efﬁciency of expanded bed adsorption. The EBA process will be more effective for those adsorbents that have both high-density base matrix and salt-tolerant ligand.
The. 32 BioProcess International Ja n ua ry B i oP r o c e ss Technical Improving Process Economy with Expanded-Bed Adsorption Technology Timo May and Kai Pohlmeyer Pr o d u c t Fo c u s: Clarifi Cation, C a p t u re Pr o c e s s Fo c u s: pr o C e s s development, p r o d u C t i o n Wh o sh o u l d re a d: pr o C e s s development Fa n d m a n u f a C t u r i n g.
The dynamic adsorption of Xe on a fixed bed adsorber at 77 K Bin Long 1,2,1), Jun- Li Li 1, Qun- Shu Wang 2, Shu- Juan Feng 2, Guo- Qing Zhou 2, Tian- Cheng Feng 2, Yan- Jie Tian 2, Huai- Cheng Ma 2 1Key Laboratory of Particle and Radiation Imaging of Ministry of Education, Department of Engineering Physics, Tsinghua University, BeijingChina 2Northwest Author: Bin Long, Jun Li Li, Qun Shu Wang, Shu Juan Feng, Guo Qing Zhou, Tian Cheng Feng, Yan Jie Tian, Huai.
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where, K YN is the rate constant (mn-1), τ is time required for 50 % adsorbate breakthrough (mn) and t is time (mn). Model of Adams-Bohart: To account for the adsorption of chlorine on a fixed bed activated carbon in a dynamic model, Bohart and Adams established the fundamental equation describing the relationship between C/C 0 and time.
The modeling conceived by .Process integration of expanded-bed adsorption with mixed-mode chromatography for protein separation 5 th International Conference and Expo on Separation Techniques.
Dong-Qiang Lin, Wei Shi, Qi-Ci Wu, Rui-Qi Yang and Shan-Jing Yao. Zhejiang University, China. ScientificTracks Abstracts: J Chromatogr Sep Tech. DOI: /CAuthor: DongQiang Lin Wei Shi QiCi Wu RuiQi Yang, ShanJing Yao.as in a cooling system. Of particular Importance is the fact that adsorption comprises the progression of two heat and mass transfer waves through a desic- cant bed.
Also important are the differences between the behavior of thick beds, typically used for industrial adsorption applications, and thin beds, as used fn desiccant cooling systems.